Sublingual Delivery of Vaccines for the Induction of Mucosal Immunity
نویسندگان
چکیده
منابع مشابه
Sublingual Delivery of Vaccines for the Induction of Mucosal Immunity
The mucosal surfaces are constantly exposed to incoming pathogens which can cause infections that result in severe morbidity and/or mortality. Studies have reported that mucosal immunity is important for providing protection against these pathogens and that mucosal vaccination is effective in preventing local infections. For many years, the sublingual mucosa has been targeted to deliver immunot...
متن کاملSublingual Delivery of Vaccines
Sublingual immunization, where the vaccine is placed directly under the tongue and absorbed through the sublingual mucosa, has the advantages of ease of delivery without the complication of oral administration or the safety concerns of intranasal vaccines. Sublingual vaccine delivery has been shown to induce development of humoral and cell mediated immunity in both the systemic and mucosal comp...
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Mucosal Immunity and Vaccines
These mucosal surfaces, while located inside the body, are actually a physical barrier between the outside and the sterile interior cavity of the body known as the “systemic” environment. Critical nutrients, oxygen and other molecules are constantly taken up across these mucosal barriers; however, another important function of the mucous is to keep invading pathogens out [15]. Daily these mucou...
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ژورنال
عنوان ژورنال: Immune Network
سال: 2013
ISSN: 1598-2629,2092-6685
DOI: 10.4110/in.2013.13.3.81